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Streptavidin (4nm) |
| Streptavidin (4nm) |
| PDMS lithography (7nm) |
| Polymer brushes (75 nm) |
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Streptavidin (4nm) |
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| Collaboration: P. Nassoy, Institut Curie, UMR 168, Paris (France) |
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| |  | | Quality control of the transfert | | | | | Rapid visualization of defects | | |
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| |  | | SiO2 Surf | | |  | | Your Optical Microscope : upright, reflected light (BF challenging, DIC mode for guaranteed success) | | | | |
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A structured PDMS stamp functionalized with streptavidin is deposited on a Surf (Whitesides method). Through hydrophilic transfer, the streptavidin gets absorbed on the surf. Without any labeling, a Sarfus optical observation allows imaging directly the pattern (grid of 4 µm*4µm) of streptavidin and its defects, which is 4nm-thick.
(scale bar: 20µm) |
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