NanoFountain Pen patterns

Nano-fountain Pen (NFP) uses a hollow capillary drawn in to a sharp tip, with an aperture of about 100 nm. The thus manufactured pipette plays the role of the AFM probe and the AFM controller drives it as it would a usual cantilever tip. When the pipette is full of solution, the liquid reaches down to the pipette tip but does not spill over. Only when physical contact with the surface is made does the writing process occur. Thus, it is possible to deliver very small amounts of solution in very precise locations. In this study, patterns (standing for the initials of Ben Gurion University) of IgG are being written by the NFP technique.

SEEC Microscopy enables rapid quality control and localisation of that particular region of interest (equally useful for AFM or Raman work). Then a complete topographic study is performed on this extremely soft sample with no contact whatsoever with no contact whatsoever and thus no risk of damage.

ROI LOCALISATION

TOPOGRAPHIC STUDY